본문
Shin, Jong Hee
| Department | Laboratory Medicine |
|---|---|
| Major Field of Research | Antifungal resistance, Epidemiology of fungal infections |
| shinjh@chonnam.ac.kr | |
| Homepage |
Research interests
Research Institute of Medical Mycology (RIMM)
Research interests of our RIMM lab lie in antifungal resistance and epidemiology of fungal infections. Our research emphasizes the importance of continued epidemiological surveillance studies to detect antifungal drug-resistant fungi, focusing on their pathogenicity, to improve the outcome of patients with fungal infections. Our current works include a) nationwide antifungal surveillance study of candidemia, b) the clinical outcomes and molecular mechanisms of antifungal resistant Candida strains, and c) development of new rapid diagnostic techniques—including techniques for candidemia detection, species identification, antifungal susceptibility testing, to enable timely administration of appropriate antifungal therapy.
Publication
- Choi MJ, Won EJ, Shin JH, et al Resistance mechanisms and clinical features of fluconazole-nonsusceptible Candida tropicalis isolates compared with fluconazole-less-susceptible isolates. Antimicrob Agents Chemother. 2016;60:3653-61
- Jung SI, Shin JH, Kim SH, et al. Comparison of E,E-Farnesol Secretion and the Clinical Characteristics of Candida albicans Bloodstream Isolates from Different Multilocus Sequence Typing Clades PLoS One. 2016:11:e0148400.
- Heo MS, Shin JH, Choi MJ, et al. Molecular identification and amphotericin B susceptibility testing of clinical isolates of Aspergillus from 11 hospitals in Korea. Ann Lab Med. 2015;35:602-10.
- Cho EJ, Shin JH, Kim SH, et al. Emergence of multiple resistance profiles involving azoles, echinocandins and amphotericin B in Candida glabrata isolates from a neutropenia patient with prolonged fungaemia. J Antimicrob Chemother.2015;70:1268-70
- Won EJ, Shin JH, Choi MJ, et al Antifungal Susceptibilities of Bloodstream Isolates of Candida Species from Nine Hospitals in Korea: Application of New Antifungal Breakpoints and Relationship to Antifungal Usage. PLoS One.2015;10:e0118770
- Lee SY, Shin JH, Kim SH, et al. Evaluation of Matrix-Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry-Based VITEK MS System for the Identification of Acinetobacter Species from Blood Cultures: Comparison with VITEK 2 and MicroScan Systems. Ann Lab Med.2015;35:62-8
- Song ES, Shin JH, Kim MN, et al. Multilocus sequence typing for the analysis of clonality among Candida albicans strains from a neonatal intensive care unit. Med Mycol.2014;52:653-8
- Won EJ, Shin JH, Lee K, et al. Evaluation of the BD Phoenix system for identification of a wide spectrum of clinically important yeast species: a comparison with Vitek 2-YST. Diagn Microbiol Infect Dis.2014;79:477-80
- Won EJ, Shin JH, Lee K, et al. Accuracy of species-level identification of yeast isolates from blood cultures from 10 university hospitals in South Korea by use of the matrix-assisted laser desorption ionization-time of flight mss spectrometry-based Vitek MS system. J Clin Microbiol. 2013;51:3063-5.
- Joo MY, Shin JH, Jang HC, et al. Expression of SAP5 and SAP9 in Candida albicans biofilms: comparison of bloodstream isolates with isolates from other sources. Med Mycol. 2013;51:892-6
- Jang MJ, Shin JH, Lee WG. et al. In Vitro Fluconazole and Voriconazole Susceptibilities of Candida Bloodstream Isolates in Korea: Use of the CLSI and EUCAST Epidemiological Cutoff Values. Ann Lab Med. 2013;33:167-73
- Park KH, Shin JH, Lee SY. et al. The clinical characteristics, carbapenem resistance, and outcome of Acinetobacter bacteremia according to genospecies. PLoS One. 2013;8:e65026
- Lee SY, Shin JH, Lee K. et al. Comparison of the Vitek 2, MicroScan, and Etest methods with the agar dilution method in assessing colistin susceptibility of bloodstream isolates of Acinetobacter species from a Korean university hospital. J Clin Microbiol. 2013;51:1924-6